Ana María Cabanas

Ana María Cabanas

Especialidad: Sistemas complejos, física médica
Ana María es PhD en Ciencias mención Física por la Universidad Complutense de Madrid y doctora en ciencias con especialización en física por la Universidad de Tarapacá. Actualmente desempeña el cargo de profesora asistente en esta última institución. Su investigación se centra en sistemas complejos y física médica, donde se requiere un enfoque interdisciplinario para la identificación de patrones y análisis de interacciones. En el ámbito docente, imparte clases desde pregrado hasta doctorado en física, matemáticas, tecnología médica y discplinas relacionadas.

PUBLICACIONES

The integration of artificial intelligence into dermatological research has underscored the need for robust and well-structured dermatological datasets. However, these datasets vary widely in their development processes, and there is currently no standard methodology to create such datasets. This work identifies three pressing needs for the building of dermatological datasets focus on skin tumor classification: the need for multimodal datasets, the definition of minimum metadata requirements, and the inclusion of underrepresented populations to address the scarcity of health data. We propose a practical methodology to create dermatological datasets from clinical records, incorporating both images and patient metadata. The process consists of four key stages: getting the institutional review board approval and analysis of clinical information sources, data recording and structuring, processing of clinical data and images, and quality assessment. This methodology was derived from hands-on experience in building two datasets from Chilean and Mexican populations, respectively. The methodology allows the creation of well-structured datasets by simplifying data organization and enabling replication. Each step includes practical guidance for dealing with typical challenges, such as image metadata categorization and technical validation by dermatologists and computer scientists. Our contribution offers a reproducible, scalable, and interdisciplinary framework for creating dermatological datasets, especially useful for countries initiating dataset creation. In addition to the methodological proposal, we highlight common pitfalls and offer recommendations to mitigate them.

Blood oxygen saturation (SpO2) is vital for patient monitoring, particularly in clinical settings. Traditional SpO2 estimation methods have limitations, which can be addressed by analyzing photoplethysmography (PPG) signals with artificial intelligence (AI) techniques. This systematic review, following PRISMA guidelines, analyzed 183 unique references from WOS, PubMed, and Scopus, with 26 studies meeting the inclusion criteria. The review examined AI models, key features, oximeters used, datasets, tested saturation intervals, and performance metrics while also assessing bias through the QUADAS-2 criteria. Linear regression models and deep neural networks (DNNs) emerged as the leading AI methodologies, utilizing features such as statistical metrics, signal-to-noise ratios, and intricate waveform morphology to enhance accuracy. Gaussian Process models, in particular, exhibited superior performance, achieving Mean Absolute Error (MAE) values as low as 0.57% and Root Mean Square Error (RMSE) as low as 0.69%. The bias analysis highlighted the need for better patient selection, reliable reference standards, and comprehensive SpO2 intervals to improve model generalizability. A persistent challenge is the reliance on non-invasive methods over the more accurate arterial blood gas analysis and the limited datasets representing diverse physiological conditions. Future research must focus on improving reference standards, test protocols, and addressing ethical considerations in clinical trials. Integrating AI with traditional physiological models can further enhance SpO2 estimation accuracy and robustness, offering significant advancements in patient care.

Pulse oximetry, although generally effective under ideal conditions, faces challenges in accurately estimating peripheral oxygen saturation (SpO2) in complex clinical scenarios, particularly at lower saturation levels and in patients with darker skin pigmentation. Artificial intelligence (AI) offers the potential to improve SpO2 monitoring by enabling more accurate, equitable, and accessible estimations. We highlight key challenges in developing AI-enhanced pulse oximetry, including the need for diverse and representative datasets, refined validation protocols addressing ethical concerns such as algorithmic bias, expanded SpO2 measurement ranges encompassing hypoxaemic levels, and enhanced model interpretability. We emphasise the importance of transitioning from subjective skin tone assessments to quantitative methods to ensure equity and mitigate bias. Finally, we propose a development pipeline and discuss strategies for robust, fair AI-based SpO2 monitoring, including aligning validation with global regulatory frameworks and fostering interdisciplinary collaboration. These advances will improve the reliability and fairness of pulse oximetry, ultimately contributing to enhanced global patient care.

Understanding how facial affect analysis (FAA) systems perform across different demographic groups requires reliable measurement of sensitive attributes such as ancestry, often approximated by skin tone, which itself is highly influenced by lighting conditions. This study compares two objective skin tone classification methods: the widely used Individual Typology Angle (ITA) and a perceptually grounded alternative based on Lightness (L^*) and Hue (H^*). Using AffectNet and a MobileNet-based model, we assess fairness across skin tone groups defined by each method. Results reveal a severe underrepresentation of dark skin tones (\sim 2 \%), alongside fairness disparities in F1-score (up to 0.08) and TPR (up to 0.11) across groups. While ITA shows limitations due to its sensitivity to lighting, the H^*-L^* method yields more consistent subgrouping and enables clearer diagnostics through metrics such as Equal Opportunity. Grad-CAM analysis further highlights differences in model attention patterns by skin tone, suggesting variation in feature encoding. To support future mitigation efforts, we also propose a modular fairness-aware pipeline that integrates perceptual skin tone estimation, model interpretability, and fairness evaluation. These findings emphasize the relevance of skin tone measurement choices in fairness assessment and suggest that ITA-based evaluations may overlook disparities affecting darker-skinned individuals.

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